Orfadin - Nitisinone - Oral Brand Drug

General Information

• Below is miscellaneous information regarding Orfadin.
• Orfadin
• nih-TIS-ih-known

Overdose

• If overdose is suspected, contact your local poison control center or emergency room immediately.

What To Do In Case Of Missed Dose

• If you miss a dose, use it as soon as you remember.
• If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule.
• Do not double the dose to catch up.

Possible Side Effects

• Headache, diarrhea, or increased thirst may occur.
• If any of these effects persist or worsen, notify your doctor.
• Tell your doctor immediately if any of these serious side effects occur.

Orfadin Miscellaneous Notes

• Do not share this medication with others.
• Laboratory and/or medical tests (for example, blood counts, eye exams, alpha-fetoprotein levels, tyrosine levels) may be performed to monitor your progress or side effects.
• It is very important to keep all regularly scheduled medical and laboratory appointments.

What To Do In Case Of Medical Emergency

• Your condition can cause complications in a medical emergency.
• For enrollment information call MedicAlert at 1-800-854-1166 (USA), or 1-800-668-1507 (Canada).

Orfadin Storage Instructions

• Store in a refrigerator between 36 and 46 degrees F (2 and 8 degrees C) away from light and moisture.

Read Before Using Orfadin (precautions)

• Tell your doctor your medical history, especially of.

Usage Instructions

• Take this medication by mouth usually twice daily on an empty stomach (at least 1 hour before meals); or as directed by your doctor.
• The dosage is based on your weight, medical condition, and response to therapy.
• If you have difficulty swallowing this medication, the capsules may be opened and the contents sprinkled into a small amount of water, formula, or applesauce immediately before use.
• Do not make up a supply in advance.

Medicinal Applications

• Nitisinone is used, along with dietary restriction of certain amino acids (tyrosine and phenylalanine), to treat a genetic metabolism disorder called hereditary tyrosinemia type 1 (HT-1).
• This condition, usually seen in children, is caused by a deficiency in an enzyme that metabolizes tyrosine.

Drug Compatibility Recommendations

• Tell your doctor of all prescription and nonprescription medication you may use.
• Do not start or stop any medicine without doctor or pharmacist approval.