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Cafergot - Ergotamine With Caffeine - Rectal Brand Drug

General Information

Take the missed dose as soon as remembered but not if it is almost time for the next dose.
If so, skip the missed dose and resume your regular schedule.
Do not "double-up" the doses.

Avoid alcohol while taking this medication as it will only make your headache worse.
Tell your doctor if you have any form of.

This drug should not be used with the following medications because very serious interactions may occur.

It is best to use this medication at the first sign of a headache.
It will take longer to work if taken when the headache has already become severe.
After using this, lie down in a quiet, dark room for an hour or two.
Do not use more than 2 suppositories per attack or more than 5 suppositories in a week.
Do not use daily on a regular basis.
Review your dosing directions with your doctor or pharmacist.
To use suppositories, unwrap it and moisten it slightly with water.
Lie on your left side with your right knee bent.
Push the suppository well into the rectum with your finger.
Try to avoid having a bowel movement for at least one hour to allow the medication to be absorbed.
Insert a second suppository if headache is not relieved after one hour.

May cause dizziness, drowsiness, stomach upset, anxiety, tremor.
These effects should subside as your body adjusts to the medication.
Avoid activities requiring alertness if dizziness or drowsiness occurs.
Tell your doctor immediately if you have any of these unlikely but serious side effects.

Infrequently, a very serious, life-threatening decrease in the amount of blood supply to the hands and feet (peripheral ischemia) and rarely to the brain can occur when this medication is taken with drugs that affect liver metabolism (for example, potent CYP 3A4 enzyme inhibitors).
Do not take this medication with macrolide antibiotics (for example, erythromycin, clarithromycin, troleandomycin), protease inhibitors (for example, ritonavir, nelfinavir, indinavir, amprenavir, saquinavir), azole antifungals (for example, ketoconazole, itraconazole).

If overdose is suspected, contact your local poison control center or emergency room immediately.
Symptoms of overdose may include nausea; diarrhea; vomiting; numbness, tingling, and bluish discoloration of fingers and toes; drowsiness; and seizures.