Xigris - Drotrecogin Alfa - Injectable Brand Drug

General Information

• Below is miscellaneous information regarding Xigris.
• Xigris
• droh-treh-KOH-gin

Usage Instructions

• Follow all instructions for proper mixing and dilution with the correct IV fluids.
• If you have any questions regarding the use of this medication, consult your pharmacist.
• When mixing this drug, do not shake the vial(s).
• Gently swirl the mixture until all the powder has dissolved.
• Shaking this drug may cause it to become ineffective.
• Because of stability issues with this drug, each dose must be made immediately before it is given.
• Give this medication by vein (IV) continuously for 4 days (96 hours) mixed in a saline solution (NS).
• Each IV bag/bottle is given over 12 hours for a total of 8 bags/bottles; or give as directed by the doctor.
• The dosage is based on your weight, medical condition, and response to therapy.
• Before using, check this product visually for particles or discoloration.
• If either is present do not use the liquid.
• Learn how to store and discard needles and medical supplies safely.
• Consult your pharmacist.

Overdose

• If overdose is suspected, stop the medication and contact your local poison control center or emergency room immediately.
• Symptoms of overdose may include.

What To Do In Case Of Missed Dose

• If a dose is stopped or interrupted, contact the doctor to establish a new dosing schedule/rate.

Drug Compatibility Recommendations

• Tell your doctor of all prescription and nonprescription medication you may use, especially.

Read Before Using Xigris (precautions)

• This medication is not recommended for use if you have the following medical conditions.

Medicinal Applications

• Drotrecogin alfa is a man-made (recombinant) form of a natural enzyme called Activated Protein C.
• It is used to treat severe/life-threatening infections in the blood (severe sepsis associated with acute organ failure).

Xigris Storage Instructions

• Store unmixed/powder vials in a refrigerator between 36 and 46 degrees F (2 and 8 degrees C) away from light.
• Do not freeze.
• Once mixed, the vials are good for 3 hours at room temperature (77 degrees F or 25 degrees C).
• Discard any unused portion of the vial(s).
• After mixing and subsequent dilution with IV fluids, this product must be used immediately and is stable at room temperature for 12 hours only.

Possible Side Effects

• No minor side effects are expected to occur.
• If any minor non-bleeding side effects occur, notify the doctor.
• Tell the doctor immediately if any of these unlikely but serious side effects occur.

Xigris Miscellaneous Notes

• Do not share this medication with others.
• Laboratory and/or medical tests may be performed to monitor your progress.