Zevalin - Ibritumomab Tiuxetan - Injectable Brand Drug

General Information

• Below is miscellaneous information regarding Zevalin.
• Zevalin
• ih-brih-TOO-mow-mab tie-ooh-X-eh-tan

Drug Compatibility Recommendations

• Tell your doctor of all prescription and nonprescription medication you may use, especially.

Zevalin Storage Instructions

• Store this product kit refrigerated between 36 and 46 degrees F (2 and 8 degrees C) away from light.
• Do not freeze.

Overdose

• If overdose is suspected, contact your local poison control center or emergency room immediately.

Warning

• A medication used along with this product (rituximab) may infrequently cause serious (sometimes fatal) side effects including severe lung problems (for example, hypoxia, pulmonary infiltrates, ARDS), heart problems (for example, cardiogenic shock, MI, ventricular fibrillation), and blood disorders (for example, cytopenias).
• These effects, if they occur, usually occur within 30 minutes to 2 hours of receiving the drug.
• Tell your doctor if you have any blood disorders, heart problems, or breathing problems before using this product and seek immediate medical attention if you develop severe trouble breathing, swelling, dizziness/lightheadedness, irregular heartbeat, or chest pain.

Possible Side Effects

• Nausea, vomiting, diarrhea, constipation, headache, stomach upset, dizziness, and/or flu-like symptoms (for example, cough, chills, muscle aches) may occur.
• If any of these effects persist or worsen, notify your doctor promptly.
• Tell your doctor immediately if any of these serious side effects occur.

Usage Instructions

• Follow all instructions for proper handling, mixing, and dilution with the correct IV fluids.
• If you have any questions regarding the use of this medication, consult the doctor or pharmacist.
• Ibritumomab is not a radioactive chemical by itself.
• There is no risk of radioactive exposure with this medication kit until it is combined with the In-111 or Y-90; all radioactive handling precautions should be followed at that time.
• The radioactive medication will be added to this drug by a properly-trained medical professional.
• Your doctor may prescribe medications to be taken 30 minutes before this drug is given.
• These drugs may help decrease the risk and/or severity of allergic reactions and some side effects.
• After being given another medication (rituximab), this medication will be injected into a vein (IV) over 10 minutes exactly as prescribed by the doctor.
• Generally, another rituximab dose is given 7 to 9 days later, followed by this medication, given IV over a 10 minute period.
• The dosage is based on your medical condition, response to therapy, and an established dosing guideline.
• Consult your doctor for details.
• Before using, check this product visually for particles or discoloration.
• If either is present, do not use the liquid.
• Learn how to store and discard needles and medical supplies safely.
• Consult your pharmacist.

What To Do In Case Of Medical Emergency

• Your condition can cause complications in a medical emergency.
• For enrollment information call MedicAlert at 1-800-854-1166 (USA), or 1-800-668-1507 (Canada).

Medicinal Applications

• Ibritumomab tiuxetan is a type of protein (monoclonal antibody plus a chelator) used, along with another monoclonal antibody (rituximab) and two radioactive pharmaceuticals (In-111 and Y-90); to treat a certain form of cancer (non-Hodgkin's lymphoma).

Zevalin Miscellaneous Notes

• Laboratory and/or medical tests (for example, blood counts, radio-imaging tests) will be performed to monitor your progress.

Read Before Using Zevalin (precautions)

• Tell your doctor your medical history, especially of.

What To Do In Case Of Missed Dose

• If you miss a dose or your dose is stopped, contact your doctor immediately to establish a new dosing schedule.